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| Title: | PYROLYTIC CARBON STUDY AS AN IMPLANTABLE MATERIAL FOR A LEFT VENTRICLE ASSIST DEVICE |
| Author: | VAN WINKLE, MICHAEL G |
| Description: | Surface wear of pyrolytic carbon, between either titanium alloy cable or cobalt chromium alloy cable, were investigated. The intent of the project is to determine the feasibility of using pyrolytic carbon as a suitable material for a left ventricle assist device (LVAD). The project studied the surface wear caused by the cables to the surface of pyrolytic carbon in a simulated in vivo experiment. A test apparatus was engineered to create an accelerated aging simulation of ratio 9:1. The project simulates 8.3% of projected lifespan of experimental implantable LVAD. In vivo experimentation was simulated by submerging the test apparatus in a dilute 0.9% NaCl saline solution held at a constant 95°F ~ 35°C. Two cables were examined, titanium alloy of 1.3 mm diameter and cobalt chromium alloy of 1.7 mm diameter. The pyrolytic carbon in contact with titanium alloy cable experienced a significantly lesser amount of wear than did the cobalt chromium. On average, the titanium alloy cable interface caused 2.155 x10-5cm3 of wear on the pyrolytic carbon chip during the course of experimentation. The cobalt chromium alloy cable interface caused 1.291 x10-3cm3 of wear. An acceptable wear for the proposed device is ~ 4.0 x10-4cm3. The titanium alloy cable interface would allow for a projected life of 35 years whereas the cobalt chromium cable interface would allow for a projected life of 2 years. Pyrolytic carbon was found to be a suitable material for a LVAD using the appropriate cable interface. |
| Permanent Link: |
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1085776125
http://hdl.handle.net/2374.OX/11765 |
| Date: | 2004 |
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