AGE-RELATED CHANGES IN PHYSICAL ACTIVITY AND BIOMARKERS OF CARDIOVASCULAR HEALTH IN FEMALE SPRAGUE-DAWLEY RATS

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Title:	AGE-RELATED CHANGES IN PHYSICAL ACTIVITY AND BIOMARKERS OF CARDIOVASCULAR HEALTH IN FEMALE SPRAGUE-DAWLEY RATS
Author:	Marker, Abigail L
Description:	Age plays a mediating role and can intensify cardiovascular health changes resulting from sedentary and physically active lifestyles. The purpose of this study was to monitor age-related changes in physical activity and biomarkers of cardiovascular health in animals provided access to: 1) a standard cage (SED), 2) 1-hr twice weekly in a large box (PA), and 3) alternate day running wheel (EX). Physical activity declined in all three groups with age. Biomarkers of cardiovascular health were maintained with age in all groups, with a few exceptions: total cholesterol and systolic blood pressure increased in SED and PA at 16 months. Animals in the EX group decreased their physical activity significantly with age, but daily activity was significantly greater compared with both PA and SED groups. Animals in PA and SED groups had extremely low activity levels throughout their life spans and showed signs of cardiovascular disease after age 16 months.
Permanent Link:	http://rave.ohiolink.edu/etdc/view?acc_num=miami1122921873 http://hdl.handle.net/2374.OX/18381
Date:	2005

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Now showing item 13 of 1238